Economics of periodic enzyme activities


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Optimal enzyme oscillations: Inducilator (speedy)

This model resembles the repressilator model, but with activating instead of inhibiting allosteric regulation. Now a wave of enzyme activity proceeds along the cycle in normal order, allowing each enzyme to peak shortly after the previous enzyme had its maximum level.

Spontaneous rhythm

Squares: enzyme levels   Circles: metabolite levels

Results (.pdf)   |   Network (.csv)