Economics of periodic enzyme activities

The following example models show that oscillations can improve enzyme efficiency in a number of ways:

Adaption to periodic reactant levels If substrates and products of a reaction vary periodically, the enzyme becomes more efficient if it oscillates in phase with the varying enzyme efficiency.
Periodic metabolite production If oscillations of a metabolite level are beneficial, enzymes that provoke such oscillations should oscillate in the right phase to make this happen.
Correlated production Of oscillations of several metabolites in phase are beneficial (for instance, as substrates of one enzyme, which then becomes more efficient), the reactions producing these metabolites should tend to oscillate accordingly.
Anti-correlated production If metabolites are supposed to oscillate out of phase (for instance, because one destroys the other), then the enzymes producing these metabolites should tend to oscillate accordingly.
Waves of activation along a pathway If an enzyme level oscillates, the level of its reaction product will oscillate and peak later. This may create an incentive for the next enzyme to oscillate as well, with a positive phase shift. This can lead to damped waves of enzyme activation along the pathway.